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US lab identifies rare new HIV strain.

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US lab identifies rare new HIV strain.
« on: November 07, 2019, 09:54:29 PM »



     This undated handout photo obtained
November 7, 2019 courtesy of Abbott
laboratories, shows Mary Rodgers, Ph.D
Principle Scientist of Infectious Disease
Research, Abbott working with samples in the
lab. – A US healthcare company has
identified a new subtype of the human
immunodeficiency virus (HIV), and said the
finding showed that cutting edge genome
sequencing is helping researchers stay ahead
of mutations. The strain, HIV-1 Group M
subtype L, has been recorded in three people
from blood samples taken between the 1980s
and 2001, all in the Democratic Republic of
Congo, Abbott laboratories told AFP on
November 7, 2019.But there is also some
evidence of subtype differences in drug
resistance. “Since subtype L is part of the
major group of HIV, Group M, I would expect
current treatments to work with it,” Mary
Rodgers, a principal scientist and head of the
Global Viral Surveillance Program at Abbott
told AFP. (Photo by HO / Abbott / AFP)
A US healthcare company has identified a
new subtype of the human immunodeficiency
virus (HIV) and said the finding showed that
cutting edge genome sequencing is helping
researchers stay ahead of mutations.
The strain, HIV-1 Group M subtype L, has
been recorded in three people from blood
samples taken between the 1980s and 2001,
all in the Democratic Republic of Congo,
Abbott laboratories told AFP on Thursday.
To classify a new subtype, three cases must
be discovered independently, according to
guidelines issued in 2000.
Group M is the most prevalent form of the
HIV-1 virus. Subtype L is now the 10th of this
group and the first to be identified since the
guidelines were issued.
Antiretroviral drugs, which reduce the viral
load of an HIV carrier to the point at which the
infection is both undetectable and cannot be
transmitted further, have generally performed
well against a variety of subtypes, according
to research.
But there is also some evidence of subtype
differences in drug resistance.
“Since subtype L is part of the major group of
HIV, Group M, I would expect current
treatments to work with it,” Mary Rodgers, a
principal scientist and head of the Global Viral
Surveillance Program at Abbott, told AFP.
She added that Abbott was making the
sequence available to the research
community to evaluate its impact on
diagnostic testing, treatments, and potential
vaccines.
“In an increasingly connected world, we can
no longer think of viruses being contained to
one location,” added Carole McArthur, a
professor of oral and craniofacial sciences at
the University of Missouri Kansas City, who
co-authored a paper on the finding in the
Journal of Acquired Immune Deficiency
Syndromes (JAIDS).
The third sample was collected 18 years ago
but was difficult to the sequence is given
technical constraints at the time.
Abbott said the breakthrough was possible
thanks to next-generation sequencing
technology that allowed scientists to build up
an entire genome at higher speed and lower
cost.
“This discovery reminds us that to end the
HIV pandemic, we must continue to outthink
this virus and use the latest advancements in
technology and resources to understand its
full scope,” said Rodgers.


https://guardian.ng/features/health/us-lab-identifies-rare-new-hiv-strain/

 
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